Understanding Dog Blood Tests

Nov. 24, 2022

Blood or lab tests allow us to obtain information about your dog's health that can only be found from collecting a sample of blood and having it analyzed. This includes a CBC (complete blood count) and blood chemistries, which analyze chemical components in the blood.


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A CBC for dogs identifies and quantifies white blood cells, red blood cells, and platelets in a given amount of blood. This includes analyzing the shape and condition of the cells for health and functionality. This provides information about your dog's immune system (white blood cells) and oxygen carrying capacity (red blood cell count).


Additionally, blood tests for dogs can also identify:

  • Glucose

  • Proteins

  • Electrolytes

  • Cholesterol

  • Endocrine levels

  • Digestive enzymes

Because chemicals found in the bloodstream can also correlate with specific organs, lab work for dogs can help determine more than just blood count. For example, if dog blood tests show a deficiency in albumin levels, then a veterinarian knows to examine the dog's liver because albumin is produced in the liver


Lab work for dogs can also detect and help to identify complex problems with body systems. For example, blood tests for dogs can detect abnormal hormonal-chemical responses to environmental and internal stimuli, which alerts a veterinarian to a potential issue with the dog's endocrine system.


So, when understood in this way, canine blood tests are very valuable tools in a veterinarian's toolkit that help to detect, identify, diagnose, and even treat illness or disease.


When Will A Veterinarian Recommend Dog Blood Tests?

The following situations can result in dog blood work being ordered:

  • On the first veterinary visit: We recommend puppies have blood tests to rule out congenital diseases, for baseline information, and for pre-anesthetic testing prior to spaying or neutering.

  • During semi-annual wellness exams: This is recommended if your veterinarian suggests it as part of a thorough physical examination because dog blood work, along with other bodily fluids like urine, can help identify conditions that the examination portion of a physical cannot.

  • If a dog seems not quite right: Canine blood tests are suitable for a dog that is not displaying any overt signs of illness, disease, or injury but is acting abnormally.

  • Pre-surgical tests: Dog blood work is used to determine the efficiency of the liver and kidneys, which helps a veterinarian select the safest dose of anesthesia. Tests can also help determine the surgical risk level in infirm, elderly, or injured dogs.

  • Prior to starting a new medication: This is particularly userful for new medications that may be metabolized by the liver or kidney.

  • During senior wellness exams: Dog blood tests are usually recommended for mature, senior, and geriatric dogs as part of their periodic wellness exams. They are extremely beneficial, as we often see senior dogs return to a more youthful state when blood tests identify an issue that can be easily treated.

Although our in-house dog laboratory can process any type of dog blood work or culture, some of the most common types of lab work for dogs we perform are:

  • Urinalysis: We evaluate your dog's urine to reveal hydration status, infections, kidney or bladder disease, diabetes, and other health conditions.

  • Fecal exam: We evaluate your dog's stool sample for color, consistency, as well as the presence of blood or mucus. We then examine it under a microscope for intestinal parasites, fungus, or protozoa.

  • Complete blood count (CBC): We analyze your dog's blood to assess features of the blood, including red and white cell count, immunity status, and the measure of hemoglobin, which is the actual substance in red blood cells that carries oxygen.

  • Blood clotting times: We test your dog's blood for bleeding disorders.

  • Blood chemistries: We identify the status of your dog's internal organs and also gauge his or her health before anesthetizing for surgery.

  • Cytology: We collect samples of sebum and cellular debris on the skin and in the ears to determine if an infection is present. In addition, we may perform needle or core biopsies of lumps or masses on your dog's body to look for cancer cells.

We recommend discussing lab tests for dogs with your veterinarian so you can make an informed decision about whether or not your canine friend can benefit from dog blood work.

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Understanding Canine Blood Tests

Understanding dog blood tests is second nature to us. However, we understand that the same might not be true for you. This is why we always fully explain the results of canine blood tests with a dog's human caretakers. Arresting and treating whatever a blood test indicates takes an informed and concerted team effort. If we are ordering dog blood work, it will most likely be in the form of a complete blood count or a blood chemistry (serum) test.


The complete blood count, or CBC, gives the veterinarian information about your dog's hydration status, anemia, infection, blood clotting ability, and immune system response. A CBC is essential for dogs that have symptoms like fever, vomiting, diarrhea, weakness, pale gums, or loss of appetite. If your dog needs surgery, a CBC can also detect bleeding disorders or other unseen abnormalities. Specifically, a CBC provides detailed information including:


  • Hematocrit (HCT): This test measures the percentage of red blood cells to detect anemia and hydration.

  • Hemoglobin and mean corpuscular hemoglobin concentration (Hb and MCHC): These are the oxygen-carrying pigments of red blood cells.

  • White blood cell count (WBC): This test measures the body's immune cells. Increases or decreases in the WBC indicate certain diseases or infections.

  • Granulocytes and lymphocytes/monocytes (GRANS and L/M): These are specific types of white blood cells.

  • Eosinophils (EOS): These are a specific type of white blood cells that may indicate allergic or parasitic conditions.

  • Platelet count (PLT): This test measures cells that form blood clots.

  • Reticulocytes (RETICS): These are immature red blood cells. High levels indicate regenerative anemia.

  • Fibrinogen (FIBR): This test provides important information about blood clotting. High levels may indicate that a dog is 30 to 40 days pregnant.

Blood chemistries, or blood serum tests, evaluate a dog's organ function, electrolyte status, hormone levels, and more. These tests are important for evaluating the health of older dogs, dogs with signs of vomiting, diarrhea, or toxin exposure, as well as dogs receiving long-term medications and general health before anesthesia.


  • Albumin (ALB): This is a serum protein that helps evaluate hydration, hemorrhage, and intestinal, liver, and kidney disease.

  • Alkaline phosphatase (ALKP): Elevations in this test may indicate liver damage, Cushing's disease, or active bone growth in a young dog.

  • Alanine aminotransferase (ALT): This test may determine active liver damage, although it does not indicate the cause.

  • Amylase (AMYL): Elevations in this test indicate pancreatitis or kidney disease.

  • Aspartate aminotransferase (AST): Increases in this test may indicate liver, heart, or skeletal muscle damage.

  • Blood urea nitrogen (BUN): This test determines kidney function. An increased level is called azotemia and can be caused by kidney, liver, and heart disease as well as urethral obstruction, shock, or dehydration.

  • Calcium (Ca): Changes in the normal level of this test can indicate a variety of diseases. Tumors, hyperparathyroidism, kidney disease, and low albumin are just a few of the conditions that alter serum calcium.

  • Cholesterol (CHOL): This test is used to supplement diagnosis of hypothyroidism, liver disease, Cushing's disease, and diabetes mellitus.

  • Chloride (Cl): Chloride is an electrolyte that is typically lost, with symptoms like vomiting or illnesses such as Addison's disease. Elevated levels often indicate dehydration.

  • Cortisol (CORT): Cortisol is a hormone that is measured in tests for Cushing's disease (the low-dose dexamethasone suppression test) and Addison's disease (ACTH stimulation test).

  • Creatinine (CREA): This test reveals kidney function and helps distinguish between kidney and non-kidney causes of elevated BUN.

  • Gamma glutamyl transferase (GGT): This is an enzyme that indicates liver disease or corticosteroid excess.

  • Globulin (GLOB): This is a blood protein that often increases with chronic inflammation and certain disease states.

  • Glucose (GLU): Glucose is a blood sugar. Elevated levels may indicate diabetes mellitus. Low levels can cause collapse, seizures, or coma.

  • Potassium (K): This is an electrolyte. Low levels may lead to symptoms such as vomiting, diarrhea, or excessive urination. Increased levels may indicate kidney failure, Addison's disease, dehydration or urethral obstruction. High levels can lead to cardiac arrest.

  • Lipase (LIP): Lipase is an enzyme that may indicate pancreatitis.

  • Sodium (Na): Sodium is an electrolyte. Low levels may lead to vomiting, diarrhea, kidney disease, and Addison's disease. This test helps indicate hydration status.

  • Phosphorus (PHOS): Elevations in this test are often associated with kidney disease, hyperthyroidism, and bleeding disorders.

  • Total bilirubin (TBIL): Elevations in this test may indicate liver or hemolytic disease. This test helps identify bile duct problems and certain types of anemia.

  • Total protein: This test indicates hydration status and provides additional information about the liver, kidneys and infectious diseases.

  • Thyroxine (T4): Thyroxine is a thyroid hormone. Decreased levels often signal hypothyroidism in dogs.

If you're concerned about your pet's health, LOCMEDT recommends that you book a consultation now. By the way, we are a clinical veterinary auto chemistry analyzer supplier. Please feel free to contact us if you need our products!

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